For me, pick-up lines are one of those genres that can only be used as a mockery of itself, but that can be good fun too.
I wouldn't recommend using any of these in real life, but if you do, remember that strangers, however geeky, may not be super into it. Respect people's personal space and what does and doesn't make them comfortable.
PS: My geek music album Borken Telephone out on Spotify! Follow Rock, Paper, Cynic and give it a listen!